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Protagonist Therapeutics - PTGX Stock Price Target and Predictions

  • Consensus Rating: Moderate Buy
  • Consensus Price Target: $82.23
  • Forecasted Upside: -5.84%
  • Number of Analysts: 14
  • Breakdown:
  • 1 Sell Ratings
  • 1 Hold Ratings
  • 11 Buy Ratings
  • 1 Strong Buy Ratings
$87.33 As of 12/4/2025 05:00 PM ET
▲ +1.26 (1.46%)

This chart shows the closing price for PTGX by one month, three months, or twelve months.

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Analyst Price Target for PTGX

Analyst Price Target is $82.23
▼ -5.84% Downside Potential
This price target is based on 14 analysts offering 12 month price targets for Protagonist Therapeutics in the last 3 months. The average price target is $82.23, with a high forecast of $112.00 and a low forecast of $38.00. The average price target represents a -5.84% upside from the last price of $87.33.

This chart shows the closing price for PTGX for the last year in relation to the current analyst high, average, and low pricetarget.

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Current Consensus is Moderate Buy

The current consensus among 14 polled investment analysts is to moderate buy stock in Protagonist Therapeutics. This rating has held steady since September 2025, when it changed from a Buy consensus rating.

Past Monthly Recommendations

Move your mouse over past months for details

Read Past Recommendations DescriptionSkip Past Price Target Consensus Chart
  • 0 strong buy ratings
  • 4 buy ratings
  • 0 hold ratings
  • 0 sell ratings
Ratings as of
6/12/2024
  • 0 strong buy ratings
  • 6 buy ratings
  • 0 hold ratings
  • 0 sell ratings
Ratings as of
9/10/2024
  • 1 strong buy ratings
  • 7 buy ratings
  • 1 hold ratings
  • 0 sell ratings
Ratings as of
12/9/2024
  • 1 strong buy ratings
  • 7 buy ratings
  • 1 hold ratings
  • 0 sell ratings
Ratings as of
3/9/2025
  • 1 strong buy ratings
  • 7 buy ratings
  • 1 hold ratings
  • 0 sell ratings
Ratings as of
6/7/2025
  • 1 strong buy ratings
  • 7 buy ratings
  • 1 hold ratings
  • 0 sell ratings
Ratings as of
9/5/2025
  • 1 strong buy ratings
  • 10 buy ratings
  • 1 hold ratings
  • 1 sell ratings
Ratings as of
11/4/2025
  • 1 strong buy ratings
  • 11 buy ratings
  • 1 hold ratings
  • 1 sell ratings
Ratings as of
12/4/2025

Latest Recommendations

  • 1 strong buy ratings
  • 11 buy ratings
  • 1 hold ratings
  • 1 sell ratings

Display Ratings By
DateBrokerageActionRatingPrice TargetDetails
11/10/2025CitigroupBoost TargetBuy ➝ Buy$96.00 ➝ $98.00
11/7/2025JPMorgan Chase & Co.Boost TargetOverweight ➝ Overweight$68.00 ➝ $81.00
11/7/2025BarclaysBoost TargetOverweight ➝ Overweight$72.00 ➝ $88.00
11/7/2025Citizens JmpBoost TargetMarket Outperform ➝ Market Outperform$69.00 ➝ $102.00
10/28/2025Truist FinancialBoost TargetBuy ➝ Buy$76.00 ➝ $88.00
10/28/2025WedbushBoost TargetOutperform ➝ Outperform$70.00 ➝ $86.00
10/28/2025BTIG ResearchReiterated RatingBuy ➝ Buy$82.00
10/17/2025CitigroupBoost TargetBuy ➝ Buy$72.00 ➝ $96.00
10/13/2025BMO Capital MarketsReiterated RatingOutperform ➝ Outperform
10/13/2025Johnson RiceSet Target$112.00
10/8/2025Weiss RatingsReiterated RatingSell (D+) ➝ Sell (D+)
10/8/2025HC WainwrightReiterated RatingBuy ➝ Buy$80.00
10/7/2025Johnson RiceSet Target$74.00
9/27/2025Weiss RatingsReiterated RatingSell (D+) ➝ Sell (D+)
9/17/2025HC WainwrightReiterated RatingBuy ➝ Buy$80.00
9/17/2025BarclaysInitiated CoverageOverweight$72.00
9/16/2025BarclaysInitiated CoverageOverweight$72.00
9/12/2025Leerink PartnrsUpgradeStrong-Buy
9/12/2025Leerink PartnersInitiated CoverageOutperform$73.00
8/7/2025CitigroupReiterated RatingOutperform ➝ Outperform
8/7/2025JMP SecuritiesBoost TargetMarket Outperform ➝ Market Outperform$67.00 ➝ $69.00
6/17/2025CitigroupInitiated CoverageBuy$72.00
6/3/2025HC WainwrightReiterated RatingBuy ➝ Buy$80.00
5/19/2025HC WainwrightReiterated RatingBuy ➝ Buy$80.00 ➝ $80.00
4/10/2025HC WainwrightReiterated RatingBuy ➝ Buy$80.00 ➝ $80.00
3/28/2025WedbushReiterated RatingOutperform ➝ Outperform$70.00 ➝ $70.00
3/11/2025WedbushReiterated RatingOutperform ➝ Outperform$70.00
3/11/2025Truist FinancialBoost TargetBuy ➝ Buy$60.00 ➝ $76.00
3/11/2025BMO Capital MarketsBoost TargetOutperform ➝ Outperform$62.00 ➝ $72.00
3/10/2025HC WainwrightReiterated RatingBuy ➝ Buy$54.00 ➝ $54.00
3/4/2025JPMorgan Chase & Co.Boost TargetOverweight ➝ Overweight$53.00 ➝ $57.00
3/3/2025BTIG ResearchSet Target$73.00
3/3/2025HC WainwrightReiterated RatingBuy ➝ Buy$54.00 ➝ $54.00
2/24/2025The Goldman Sachs GroupLower TargetNeutral ➝ Neutral$43.00 ➝ $38.00
2/24/2025HC WainwrightBoost TargetBuy ➝ Buy$50.00 ➝ $54.00
2/21/2025WedbushReiterated RatingOutperform$58.00
2/7/2025JMP SecuritiesReiterated RatingMarket Outperform ➝ Market Outperform$58.00 ➝ $58.00
2/7/2025HC WainwrightReiterated RatingBuy ➝ Buy$50.00 ➝ $50.00
2/4/2025JPMorgan Chase & Co.Boost TargetOverweight ➝ Overweight$51.00 ➝ $53.00
12/10/2024HC WainwrightReiterated RatingBuy ➝ Buy$50.00 ➝ $50.00
12/6/2024The Goldman Sachs GroupInitiated CoverageNeutral$47.00
12/6/2024BMO Capital MarketsInitiated CoverageOutperform$62.00
12/5/2024The Goldman Sachs GroupUpgradeHold
11/19/2024WedbushReiterated RatingOutperform$58.00
11/19/2024HC WainwrightReiterated RatingBuy ➝ Buy$50.00 ➝ $50.00
11/11/2024HC WainwrightReiterated RatingBuy ➝ Buy$50.00 ➝ $50.00
11/4/2024WedbushReiterated RatingOutperform$58.00
9/25/2024TD CowenUpgradeStrong-Buy
9/24/2024TD CowenInitiated CoverageBuy$65.00
9/12/2024HC WainwrightBoost TargetBuy ➝ Buy$40.00 ➝ $50.00
9/9/2024Truist FinancialInitiated CoverageBuy$60.00
8/7/2024HC WainwrightBoost TargetBuy ➝ Buy$38.00 ➝ $40.00
8/7/2024JMP SecuritiesLower TargetMarket Outperform ➝ Market Outperform$45.00 ➝ $43.00
7/25/2024JPMorgan Chase & Co.Boost TargetOverweight ➝ Overweight$39.00 ➝ $48.00
7/24/2024BTIG ResearchBoost TargetBuy ➝ Buy$41.00 ➝ $51.00
6/17/2024JMP SecuritiesReiterated RatingMarket Outperform ➝ Market Outperform$45.00 ➝ $45.00
6/14/2024HC WainwrightReiterated RatingBuy ➝ Buy$38.00 ➝ $38.00
5/9/2024HC WainwrightReiterated RatingBuy ➝ Buy$38.00
5/8/2024JMP SecuritiesBoost TargetMarket Outperform ➝ Market Outperform$42.00 ➝ $45.00
2/28/2024JPMorgan Chase & Co.Boost TargetOverweight ➝ Overweight$34.00 ➝ $37.00
2/28/2024HC WainwrightReiterated RatingBuy ➝ Buy$38.00
11/3/2023JMP SecuritiesBoost TargetMarket Outperform ➝ Market Outperform$35.00 ➝ $37.00
10/30/2023Capital One FinancialInitiated CoverageOverweight$32.00
10/10/2023HC WainwrightReiterated RatingBuy ➝ Buy$38.00
9/25/2023JPMorgan Chase & Co.Lower TargetOverweight ➝ Overweight$36.00 ➝ $34.00
8/4/2023HC WainwrightReiterated RatingBuy ➝ Buy$38.00
7/6/2023JMP SecuritiesBoost Target$28.00 ➝ $35.00
3/16/2023JMP SecuritiesLower TargetMarket Outperform$31.00 ➝ $28.00
3/16/2023HC WainwrightBoost TargetBuy$33.00 ➝ $38.00
3/8/2023JMP SecuritiesBoost TargetMarket Outperform$21.00 ➝ $31.00
11/16/2022BTIG ResearchLower Target$41.00
11/10/2022HC WainwrightLower TargetBuy$50.00 ➝ $33.00
8/25/2022JMP SecuritiesInitiated CoverageOutperform$21.00
5/17/2022Piper SandlerLower TargetOverweight$60.00 ➝ $35.00
4/26/2022BTIG ResearchLower Target$55.00 ➝ $45.00
4/14/2022BTIG ResearchReiterated RatingBuy$55.00
2/11/2022BTIG ResearchInitiated CoverageBuy$55.00
11/15/2021JMP SecuritiesBoost TargetPositive ➝ Outperform$60.00 ➝ $70.00
10/13/2021JMP SecuritiesBoost TargetHold ➝ Outperform$47.00 ➝ $60.00
10/12/2021Leerink PartnersBoost TargetOutperform$35.00 ➝ $50.00
10/12/2021JPMorgan Chase & Co.UpgradeNeutral ➝ Overweight$49.00 ➝ $55.00
10/11/2021Jefferies Financial GroupBoost TargetHold ➝ Buy$29.00 ➝ $60.00
10/11/2021Northland SecuritiesUpgradeMarket Perform ➝ Outperform$40.00
9/22/2021JMP SecuritiesLower TargetMarket Outperform$55.00 ➝ $47.00
9/20/2021HC WainwrightReiterated RatingBuy$60.00 ➝ $50.00
9/20/2021JPMorgan Chase & Co.DowngradeOverweight ➝ Neutral$60.00 ➝ $49.00
9/17/2021JMP SecuritiesReiterated RatingHold ➝ Buy$47.00 ➝ $55.00
8/6/2021HC WainwrightBoost TargetBuy$50.00 ➝ $60.00
8/5/2021Leerink PartnersBoost TargetOutperform$41.00 ➝ $50.00
7/30/2021Piper SandlerBoost TargetOverweight$53.00 ➝ $93.00
6/18/2021HC WainwrightBoost TargetBuy$36.00 ➝ $50.00
6/14/2021Northland SecuritiesBoost TargetOutperform$42.00 ➝ $47.00
5/24/2021JMP SecuritiesInitiated CoverageMarket Outperform$48.00
5/24/2021Northland SecuritiesInitiated CoverageOutperform$42.00
3/11/2021HC WainwrightBoost TargetBuy$33.00 ➝ $36.00
3/3/2021Leerink PartnersBoost TargetPositive ➝ Outperform$30.00 ➝ $41.00
1/6/2021JPMorgan Chase & Co.Initiated CoverageOverweight$35.00
12/16/2020Piper SandlerInitiated CoverageOverweight$53.00
12/7/2020BMO Capital MarketsBoost Target$37.00 ➝ $46.00
(Data available from 12/4/2020 forward)

News Sentiment Rating

1.14 (Buy)

Our news sentiment rating is based on the average sentiment of articles about this company published in the media in the last 30 days of headlines and can range from 2 (very positive sentiment) to -2 (very negative sentiment).

News Sentiment Over Time

Move your mouse over past months for details

Skip to Current Sentiment Summary
  • 32 very positive mentions
  • 7 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
5/8/2025
  • 29 very positive mentions
  • 6 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
6/7/2025
  • 10 very positive mentions
  • 8 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
7/7/2025
  • 24 very positive mentions
  • 2 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
8/6/2025
  • 31 very positive mentions
  • 4 positive mentions
  • 1 negative mentions
  • 0 very negative mentions
Mentions as of
9/5/2025
  • 25 very positive mentions
  • 19 positive mentions
  • 2 negative mentions
  • 0 very negative mentions
Mentions as of
10/5/2025
  • 16 very positive mentions
  • 30 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
11/4/2025
  • 26 very positive mentions
  • 16 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
Mentions as of
12/4/2025

Current Sentiment

  • 26 very positive mentions
  • 16 positive mentions
  • 0 negative mentions
  • 0 very negative mentions

Recent Stories by Sentiment

Very Negative

  • No very negative mentions tracked during this time.

Negative

  • No negative mentions tracked during this time.

Positive

Very Positive

Protagonist Therapeutics logo
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
Read More

Today's Range

Now: $87.33
Low: $85.13
High: $88.10

50 Day Range

MA: $78.32
Low: $64.00
High: $90.07

52 Week Range

Now: $87.33
Low: $33.70
High: $93.25

Volume

736,770 shs

Average Volume

862,927 shs

Market Capitalization

$5.46 billion

P/E Ratio

140.86

Dividend Yield

N/A

Beta

2.19

Frequently Asked Questions

What sell-side analysts currently cover shares of Protagonist Therapeutics?

The following equities research analysts have issued research reports on Protagonist Therapeutics in the last year: Barclays PLC, BMO Capital Markets, BTIG Research, Citigroup Inc., Citizens Jmp, HC Wainwright, JMP Securities, Johnson Rice, JPMorgan Chase & Co., Leerink Partners, Leerink Partnrs, The Goldman Sachs Group, Inc., Truist Financial Corporation, Wall Street Zen, Wedbush, and Weiss Ratings.
View the latest analyst ratings for PTGX.

What is the current price target for Protagonist Therapeutics?

0 Wall Street analysts have set twelve-month price targets for Protagonist Therapeutics in the last year. Their average twelve-month price target is $82.23, suggesting a possible downside of 5.8%. Johnson Rice has the highest price target set, predicting PTGX will reach $112.00 in the next twelve months. The Goldman Sachs Group, Inc. has the lowest price target set, forecasting a price of $38.00 for Protagonist Therapeutics in the next year.
View the latest price targets for PTGX.

What is the current consensus analyst rating for Protagonist Therapeutics?

Protagonist Therapeutics currently has 1 sell rating, 1 hold rating, 11 buy ratings and 1 strong buy rating from Wall Street analysts. The stock has a consensus analyst rating of "Moderate Buy."
View the latest ratings for PTGX.

What other companies compete with Protagonist Therapeutics?

Other companies that are similar to Protagonist Therapeutics include Genmab A/S, Revolution Medicines, Roivant Sciences, Summit Therapeutics and BridgeBio Pharma. Learn More about companies similar to Protagonist Therapeutics.

How do I contact Protagonist Therapeutics' investor relations team?

Protagonist Therapeutics' physical mailing address is 7707 GATEWAY BOULEVARD SUITE 140, NEWARK CA, 94560. The company's listed phone number is (510) 474-0170 and its investor relations email address is [email protected]. The official website for Protagonist Therapeutics is www.protagonist-inc.com. Learn More about contacing Protagonist Therapeutics investor relations.