NASDAQ:IONS - Ionis Pharmaceuticals Stock Price Target and Predictions

  • Consensus Rating: Hold
  • Consensus Price Target: $45.50
  • Forecasted Upside: 0.35 %
  • Number of Analysts: 10
  • Breakdown:
  • 3 Sell Ratings
  • 1 Hold Ratings
  • 6 Buy Ratings
  • 0 Strong Buy Ratings
▼ -0.77 (-1.67%)

This chart shows the closing price for IONS by one month, three months, or twelve months.

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Analyst Price Target for IONS

Analyst Price Target is $45.50
▲ +0.35% Upside Potential
This price target is based on 10 analysts offering 12 month price targets for Ionis Pharmaceuticals in the last 3 months. The average price target is $45.50, with a high forecast of $65.00 and a low forecast of $27.00. The average price target represents a 0.35% upside from the last price of $45.34.

This chart shows the closing price for IONS for the last year in relation to the current analyst high, average, and low pricetarget.

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Current Consensus is Hold

The current consensus among 10 investment analysts is to hold stock in Ionis Pharmaceuticals. This Hold consensus rating has held steady for over two years.

Past Monthly Recommendations

Move your mouse over past months for details

Read Past Recommendations DescriptionSkip Past Price Target Consensus Chart
  • 0 strong buy ratings
  • 6 buy ratings
  • 5 hold ratings
  • 2 sell ratings
  • 0 strong buy ratings
  • 7 buy ratings
  • 6 hold ratings
  • 2 sell ratings
  • 0 strong buy ratings
  • 6 buy ratings
  • 6 hold ratings
  • 1 sell ratings
  • 0 strong buy ratings
  • 5 buy ratings
  • 3 hold ratings
  • 1 sell ratings
  • 0 strong buy ratings
  • 5 buy ratings
  • 3 hold ratings
  • 2 sell ratings
  • 0 strong buy ratings
  • 4 buy ratings
  • 1 hold ratings
  • 3 sell ratings
  • 0 strong buy ratings
  • 4 buy ratings
  • 1 hold ratings
  • 3 sell ratings
  • 0 strong buy ratings
  • 6 buy ratings
  • 1 hold ratings
  • 3 sell ratings

Latest Recommendations

  • 0 strong buy ratings
  • 6 buy ratings
  • 1 hold ratings
  • 3 sell ratings

Display Ratings By
DateBrokerageActionRatingPrice TargetImpact on Share PriceDetails
8/10/2022CitigroupBoost Price TargetSell$26.00 ➝ $28.00Low
7/26/2022Piper SandlerBoost Price TargetOverweight$55.00 ➝ $58.00Low
7/18/2022OppenheimerReiterated RatingOutperform$59.00Low
6/21/2022SVB LeerinkBoost Price TargetMarket Perform$26.00 ➝ $27.00Low
6/10/2022Piper SandlerBoost Price Target$54.00 ➝ $55.00High
5/5/2022Stifel NicolausBoost Price Target$31.00 ➝ $33.00Low
4/1/2022SVB LeerinkLower Price TargetMarket Perform$29.00 ➝ $26.00High
3/1/2022GuggenheimInitiated CoverageBuy$64.00Medium
2/28/2022CitigroupInitiated CoverageSell$26.00Medium
2/25/2022SVB LeerinkLower Price TargetMarket Perform$34.00 ➝ $29.00Medium
2/1/2022Bank of AmericaDowngradeBuy ➝ Underperform$40.00 ➝ $30.00High
12/17/2021SVB LeerinkLower Price TargetMarket Perform$36.00 ➝ $34.00High
12/14/2021William BlairUpgradeMarket Perform ➝ OutperformHigh
12/10/2021BMO Capital MarketsInitiated CoverageBuy$65.00Medium
12/8/2021SVB LeerinkLower Price TargetMarket Perform$39.00 ➝ $36.00High
11/4/2021Needham & Company LLCLower Price TargetBuy$84.00 ➝ $60.00Medium
11/4/2021SVB LeerinkBoost Price TargetMarket Perform$38.00 ➝ $39.00Medium
10/12/2021Morgan StanleyLower Price TargetUnderweight$33.00 ➝ $31.00Low
8/19/2021BMO Capital MarketsLower Price TargetOutperform$70.00 ➝ $68.00Low
8/5/2021SVB LeerinkLower Price TargetMarket Perform$41.00 ➝ $38.00High
7/16/2021Morgan StanleyLower Price TargetUnderweight$35.00 ➝ $33.00Medium
5/14/2021SVB LeerinkBoost Price TargetMarket Perform$36.00 ➝ $41.00Medium
5/7/2021UBS GroupUpgradeSell ➝ Neutral$33.00 ➝ $37.50High
5/6/2021Morgan StanleyLower Price TargetUnderweight$38.00 ➝ $35.00High
4/19/2021Morgan StanleyLower Price TargetUnderweight$43.00 ➝ $38.00Low
4/5/2021UBS GroupReiterated RatingReduceHigh
3/23/2021BMO Capital MarketsLower Price TargetPositive ➝ Outperform$90.00 ➝ $76.00High
3/23/2021Needham & Company LLCLower Price TargetBuy$95.00 ➝ $86.00High
3/23/2021SVB LeerinkLower Price TargetMarket Perform$50.00 ➝ $36.00High
3/23/2021Morgan StanleyLower Price TargetUnderweight$50.00 ➝ $43.00High
3/23/2021BarclaysLower Price TargetEqual Weight$52.00 ➝ $47.00High
3/23/2021Royal Bank of CanadaLower Price TargetPositive ➝ Outperform$76.00 ➝ $65.00High
3/22/2021Piper SandlerLower Price TargetNeutral$55.00 ➝ $45.00High
3/16/2021UBS GroupReiterated RatingSell$33.00Medium
3/1/2021BarclaysUpgradeUnderweight ➝ Equal Weight$50.00 ➝ $52.00Low
2/25/2021Morgan StanleyBoost Price TargetUnderweight$49.00 ➝ $50.00High
2/24/2021Piper SandlerLower Price TargetNeutral$60.00 ➝ $55.00High
12/15/2020UBS GroupInitiated CoverageSell$34.00Medium
12/15/2020CowenUpgradeMarket Perform ➝ OutperformHigh
11/5/2020Morgan StanleyLower Price TargetUnderweight$50.00 ➝ $49.00High
11/5/2020SVB LeerinkLower Price TargetMarket Perform$56.00 ➝ $50.00High
10/13/2020Morgan StanleyLower Price TargetUnderweight$54.00 ➝ $50.00Low
10/7/2020OppenheimerReiterated RatingBuy$69.00Low
9/22/2020OppenheimerInitiated CoverageBuy$69.00High
9/22/2020Cantor FitzgeraldBoost Price TargetNeutral$56.00 ➝ $59.00High
9/14/2020JPMorgan Chase & Co.Initiated CoverageNeutralMedium
9/8/2020CitigroupLower Price Target$74.00 ➝ $78.00Low
9/2/2020BenchmarkInitiated CoverageHoldMedium
9/1/2020Royal Bank of CanadaBoost Price Target$71.00 ➝ $73.00Low
9/1/2020SVB LeerinkBoost Price TargetMarket Perform$54.00 ➝ $56.00Medium
9/1/2020OppenheimerLower Price TargetOutperform$74.00 ➝ $69.00Medium
9/1/2020Needham & Company LLCBoost Price TargetBuy$89.00 ➝ $91.00Medium
8/30/2020OppenheimerInitiated CoverageBuy$74.00High
8/10/2020CitigroupLower Price TargetBuy$80.00 ➝ $78.00High
8/6/2020Morgan StanleyLower Price TargetUnderweight$56.00 ➝ $54.00Low
8/6/2020OppenheimerReiterated RatingBuyLow
8/5/2020Needham & Company LLCInitiated CoverageBuy$89.00Low
8/5/2020William BlairReiterated RatingHoldLow
7/15/2020Morgan StanleyBoost Price TargetUnderweight$51.00 ➝ $56.00Low
7/15/2020Needham & Company LLCReiterated RatingBuy$89.00Medium
6/10/2020William BlairReiterated RatingHoldHigh
6/5/2020CitigroupBoost Price TargetBuy$71.00 ➝ $80.00High
5/12/2020Royal Bank of CanadaInitiated CoverageOutperform$71.00Medium
5/7/2020Morgan StanleyBoost Price TargetUnderweight$48.00 ➝ $51.00High
5/7/2020OppenheimerLower Price TargetOutperform$77.00 ➝ $74.00High
5/6/2020Needham & Company LLCReiterated RatingBuy$89.00High
4/9/2020CitigroupLower Price TargetBuy$73.00 ➝ $71.00Low
3/26/2020Cantor FitzgeraldLower Price TargetNeutral$65.00 ➝ $56.00High
3/9/2020JPMorgan Chase & Co.Boost Price TargetNeutral$58.00 ➝ $60.00Low
3/5/2020CitigroupInitiated CoverageBuy$73.00High
2/27/2020Piper SandlerLower Price TargetNeutral$70.00 ➝ $65.00High
1/30/2020BMO Capital MarketsReiterated RatingBuy$86.00High
1/24/2020William BlairReiterated RatingHoldLow
12/31/2019Bank of AmericaReiterated RatingBuy$70.00Medium
12/23/2019Needham & Company LLCReiterated RatingBuy$87.00Low
12/13/2019Needham & Company LLCReiterated RatingBuy$87.00Medium
12/12/2019OppenheimerInitiated CoverageBuy$77.00Low
11/14/2019William BlairInitiated CoverageMarket PerformLow
11/13/2019Bank of AmericaInitiated CoverageBuy$70.00Medium
11/7/2019Piper Jaffray CompaniesLower Price TargetNeutral$75.00 ➝ $70.00Medium
11/7/2019Needham & Company LLCReiterated RatingBuy$87.00Low
11/7/2019Morgan StanleyDowngradeEqual ➝ Equal Weight$63.00 ➝ $48.00Low
11/7/2019CowenReiterated RatingHoldLow
10/16/2019CowenReiterated RatingHoldHigh
10/15/2019Cantor FitzgeraldSet Price TargetHold$65.00N/A
10/11/2019Morgan StanleyLower Price TargetEqual Weight$68.00 ➝ $63.00Medium
10/10/2019Wells Fargo & CompanyBoost Price TargetOutperform$90.00 ➝ $120.00Medium
10/9/2019Needham & Company LLCSet Price TargetBuy$87.00Low
9/23/2019Wells Fargo & CompanyReiterated RatingBuyMedium
9/10/2019Sanford C. BernsteinUpgradeMarket Perform ➝ Outperform$80.00High
8/7/2019Evercore ISISet Price TargetHold$76.00Low
7/24/2019BMO Capital MarketsLower Price TargetOutperform$96.00 ➝ $95.00Low
5/24/2019Piper Jaffray CompaniesSet Price TargetHold$75.00Medium
4/24/2019Cantor FitzgeraldReiterated RatingHold$68.00Low
4/22/2019BMO Capital MarketsBoost Price TargetOutperform$96.00Low
4/18/2019Cantor FitzgeraldReiterated RatingHoldLow
4/9/2019Cantor FitzgeraldInitiated CoverageNeutral$68.00Medium
3/22/2019Piper Jaffray CompaniesSet Price TargetNeutral$63.00 ➝ $75.00Low
3/18/2019JPMorgan Chase & Co.Boost Price TargetNeutral ➝ Neutral$47.00 ➝ $55.00Low
3/1/2019Morgan StanleySet Price TargetHold$71.00Low
3/1/2019Piper Jaffray CompaniesSet Price TargetHold$63.00Low
2/28/2019Piper Jaffray CompaniesBoost Price TargetNeutral$60.00Low
2/28/2019BMO Capital MarketsBoost Price TargetOutperform ➝ Outperform$70.00 ➝ $82.00Low
11/27/2018SVB LeerinkInitiated CoverageMarket Perform$50.00High
11/7/2018Morgan StanleySet Price TargetHold$46.00Low
11/6/2018Piper Jaffray CompaniesSet Price TargetHold$50.00Medium
10/3/2018Morgan StanleySet Price TargetHold$45.00Low
9/25/2018Stifel NicolausBoost Price TargetHold ➝ Hold$45.00 ➝ $48.00High
9/24/2018Piper Jaffray CompaniesSet Price TargetHold$50.00Medium
8/28/2018Morgan StanleyLower Price TargetEqual Weight ➝ Equal Weight$49.00 ➝ $45.00Low
8/28/2018Stifel NicolausLower Price TargetHold ➝ Hold$47.00 ➝ $45.00High
8/8/2018Morgan StanleyLower Price TargetEqual Weight ➝ Equal Weight$51.00 ➝ $49.00High
8/7/2018Stifel NicolausLower Price TargetHold ➝ Hold$55.00 ➝ $48.00High
7/11/2018Piper Jaffray CompaniesSet Price TargetHold$50.00Low
6/20/2018BarclaysDowngradeEqual Weight ➝ Underweight$52.00High
5/30/2018Piper Jaffray CompaniesInitiated CoverageHold$50.00Medium
5/7/2018Morgan StanleyLower Price TargetEqual Weight ➝ Equal Weight$52.00Low
5/7/2018Stifel NicolausLower Price TargetHold ➝ Hold$57.00Low
4/23/2018BMO Capital MarketsBoost Price TargetOutperform ➝ Outperform$70.00 ➝ $75.00Medium
2/28/2018BMO Capital MarketsBoost Price TargetOutperform ➝ Outperform$64.00 ➝ $65.00High
2/28/2018Stifel NicolausBoost Price TargetHold ➝ Hold$55.00 ➝ $57.00High
2/20/2018Sanford C. BernsteinReiterated RatingMarket Perform$61.00 ➝ $55.00Low
11/8/2017BMO Capital MarketsBoost Price TargetOutperform$64.00 ➝ $65.00N/A
11/8/2017Morgan StanleyBoost Price TargetEqual Weight$45.00 ➝ $49.00N/A
10/17/2017Needham & Company LLCReiterated RatingBuy$64.00N/A
10/13/2017Stifel NicolausReiterated RatingHold$50.00N/A
10/6/2017The Goldman Sachs GroupReiterated RatingSell ➝ Sell$30.00N/A
10/2/2017BMO Capital MarketsReiterated RatingOutperform$69.00Medium
9/21/2017BarclaysLower Price TargetEqual Weight$55.00 ➝ $52.00Low
9/17/2017Needham & Company LLCReiterated RatingBuy$64.00Low
9/12/2017Stifel NicolausReiterated RatingHoldLow
9/6/2017BarclaysInitiated CoverageEqual Weight$55.00Medium
8/16/2017Evercore ISIInitiated CoverageOutperform ➝ Outperform$65.00Low
8/14/2017LaidlawReiterated RatingBuy$65.00Low
8/14/2017BMO Capital MarketsBoost Price TargetOutperform$67.00 ➝ $69.00Low
(Data available from 8/11/2017 forward)

News Sentiment Rating

0.42 (Hold)

Our news sentiment rating is based on the average sentiment of articles about this company published in the media in the last 30 days of headlines and can range from 2 (very positive sentiment) to -2 (very negative sentiment).

News Sentiment Over Time

Move your mouse over past months for details

Skip to Current Sentiment Summary
  • 2 very positive mentions
  • 11 positive mentions
  • 0 negative mentions
  • 0 very negative mentions
  • 3 very positive mentions
  • 13 positive mentions
  • 4 negative mentions
  • 1 very negative mentions
  • 2 very positive mentions
  • 4 positive mentions
  • 2 negative mentions
  • 0 very negative mentions
  • 4 very positive mentions
  • 4 positive mentions
  • 5 negative mentions
  • 0 very negative mentions
  • 0 very positive mentions
  • 11 positive mentions
  • 1 negative mentions
  • 0 very negative mentions
  • 0 very positive mentions
  • 6 positive mentions
  • 1 negative mentions
  • 0 very negative mentions
  • 9 very positive mentions
  • 3 positive mentions
  • 1 negative mentions
  • 0 very negative mentions
  • 5 very positive mentions
  • 24 positive mentions
  • 2 negative mentions
  • 1 very negative mentions

Current Sentiment

  • 5 very positive mentions
  • 24 positive mentions
  • 2 negative mentions
  • 1 very negative mentions
Ionis Pharmaceuticals logo
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of TTR amyloidosis; Olezarsen for patients with severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Tofersen to inhibit the production of superoxide dismutase 1. In addition, the company develops medicines for metabolic diseases, infectious diseases, renal diseases, ophthalmic diseases, and cancer. It has a strategic collaboration with Biogen Inc.; and collaboration and license agreement with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc. Ionis Pharmaceuticals, Inc. was founded in 1989 and is based in Carlsbad, California.
Read More

Today's Range

Now: $45.34
Low: $45.34
High: $46.13

50 Day Range

MA: $37.90
Low: $33.50
High: $46.11

52 Week Range

Now: $45.34
Low: $25.04
High: $46.15


3,407 shs

Average Volume

932,855 shs

Market Capitalization

$6.43 billion

P/E Ratio


Dividend Yield




Frequently Asked Questions

What sell-side analysts currently cover shares of Ionis Pharmaceuticals?

The following equities research analysts have issued research reports on Ionis Pharmaceuticals in the last year: Bank of America Co., BMO Capital Markets, Citigroup Inc., Guggenheim, Morgan Stanley, Needham & Company LLC, Oppenheimer Holdings Inc., Piper Sandler, Stifel Nicolaus,, SVB Leerink LLC, TheStreet, and William Blair.
View the latest analyst ratings for IONS.

What is the current price target for Ionis Pharmaceuticals?

10 Wall Street analysts have set twelve-month price targets for Ionis Pharmaceuticals in the last year. Their average twelve-month price target is $45.50, suggesting a possible upside of 0.4%. BMO Capital Markets has the highest price target set, predicting IONS will reach $65.00 in the next twelve months. SVB Leerink LLC has the lowest price target set, forecasting a price of $27.00 for Ionis Pharmaceuticals in the next year.
View the latest price targets for IONS.

What is the current consensus analyst rating for Ionis Pharmaceuticals?

Ionis Pharmaceuticals currently has 3 sell ratings, 1 hold rating and 6 buy ratings from Wall Street analysts. The stock has a consensus analyst rating of "Hold." A "hold" rating indicates that analysts believe investors should keep any existing positions they have in IONS, but not buy more shares or sell existing shares.
View the latest ratings for IONS.

What other companies compete with Ionis Pharmaceuticals?

How do I contact Ionis Pharmaceuticals' investor relations team?

Ionis Pharmaceuticals' physical mailing address is 2855 GAZELLE COURT, CARLSBAD CA, 92010. The company's listed phone number is (760) 931-9200 and its investor relations email address is [email protected] The official website for Ionis Pharmaceuticals is Learn More about contacing Ionis Pharmaceuticals investor relations.